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SPILLAGE MANAGEMENT IN PHARMACEUTICAL PRODUCTION AREA Pharmaceutical production is a highly complex and demanding process that requires careful management of resources. One of the key areas where effective spillage management is essential is in the pharmaceutical production area. In this article, we will explore the different types of spillages that can occur in this environment and discuss the best ways to manage them. Causes of Spillage  Spillage is caused when products, solutions and wastes are released from equipment, containers, or vessels. In pharmaceutical production, spills can be caused by a variety of reasons including:  Incorrect use of equipment or procedures  Faulty manufacturing processes  Engineering errors  Poor maintenance  Operational deficiencies  Personnel mistakes The most common sources of pharmaceutical spills are the storage and handling of product and solution containers. Solutions may also leak from vessels used in drug manufa...

Pharmaceutical Facilities to maintain an Aseptic Area?  Aseptic areas are used in the pharmaceutical industry for creating sterile and controlled environments. Clean rooms must be constantly maintained by following strict procedures, including daily cleaning and disinfecting.  Aseptic conditions are a crucial part of any sterile area and keeping them up to date can be challenging. This article discusses the various aspects of Aseptic maintenance.  What are Aseptic Facilities?  Aseptic facilities are those that maintain sterile conditions to prevent the spread of contamination. These facilities must meet regulatory requirements set by the US Food and Drug Administration (FDA), European Medicines Agency (EMA), and other regulatory authorities. Sterile areas in a manufacturing plant can include operating rooms, clean rooms, laboratories, and storage areas. To maintain sterile conditions, aseptic facilities must have strict policies and procedures in place. These policie...

 Air handling unit Air handling unit is an important equipment in the pharmaceutical industry. It is used to control the environment inside the cleanroom. The process of handling air in pharmaceuticals is critical to ensuring the quality and safety of the products being manufactured. In this article, we'll take a look at how air handling units work in pharmaceuticals to ensure that the products being made meet the highest standards.  The Principle and Working of Air Handling Units Air handling unit is an important equipment in the pharmaceutical industry. It is used to control the environment inside the cleanroom. The unit can be used to adjust the temperature, humidity and air pressure. It also filters the air to remove contaminants. The working principle of the air handling unit is based on the laws of thermodynamics and fluid dynamics.  The unit uses a fan to draw air from the outside and then passes it through a series of filters. The air is then cooled or heated as r...

  F0 Value (Equivalent Exposure Time) F0 value is the equivalent exposure time at 121.1°C to that of the actual exposure time at a variable temperature calculated with a temperature coefficient of the destruction of 10°C. F0 Value Definition F0 Value (Equivalent Exposure Time) where, Δt – the time interval between two temperature readings T – the temperature at time t of the product under sterilization z – temperature coefficient (assumed as 10°C) The term next to Δt in equation (2) is called Lethality Rate. You can calculate it individually or by averaging complete sterile hold data, the result will be equivalent. Testing F0 Value And Its Meaning Consider sterilization hold time of 30 min. at constant 121.1°C. Put this in equation (2), Solving we get, F0 = 30 min. ( This is an ideal condition for steam sterilization ) But what if the temperature is increased or decreased from 121°C (ideal condition)? Let...

 घर बैठे पैसे कमाएं क्या आप जानते है कि आप घर बैठे अपने मोबाईल से पैसे कमा सकते हैं? जी हां आपने बिल्कुल सही सुना, आप कमा सकते हैं घर बैठे पैसे वो भी सिर्फ 5 से 10 मिनट का काम करके। आपके मोबाईल बहुत सारे विज्ञापन आते होंगे लेकिन उन्हें देखने पर आपको कुछ नही मिलता है लेकिन एक एप जिसका नाम है एड्स एक्सचेंज उसमे रोजाना सिर्फ 20 एड्स को देख कर आपको मिलेंगे कम से कम 40 रुपए प्रति दिन और अगर आप किसी को अपनी आईडी से जोड़ते हैं तो आपको टीम से भी रुपए मिलेंगे  कैसे होगा रजिस्ट्रेशन रजिस्टर करने के लिए नीचे दिए गए लिंक पर जाएं और अपनी मेल आईडी और मोबाइल नंबर से रजिस्टर करें जिसके बाद आपको अपनी आईडी, पासवर्ड और पिन नंबर मिलेगा उसे संभाल कर रखिए और लॉगिन करने के लिए लॉगिन वाले लिंक पर जाकर लॉगिन करें। रजिस्ट्रेशन के लिए लिंक https://www.adsexchange.in/signup/AD89214950 लॉगिन करने के लिए लिंक https://www.adsexchange.in/signin लॉगिन करने के बाद आपको अपनी आईडी को लाइफटाइम के लिए एक्टिवेट करना होगा जिसके लिए आपको 1000रुपए से टॉप अप करना होगा, फिर आप जिंदगी भर कम से कम 40 रुपए रोज कमा सकते हैं...

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  Difference Between Beta Lactam and Non Beta Lactam The key difference between beta lactam and non beta lactam is that the beta lactam antibiotics contain a beta lactam ring in their molecular structure while the non beta lactam antibiotics do not contain a beta lactam ring in their molecular structure. Antibiotics are antimicrobial drugs that prevent bacterial infections. There is a wide variety of antibiotics. These medications revolutionized the medicine. Some antibiotics kill bacteria powerfully while some inhibit the growth and reproduction of bacteria. However, bacteria have gained antibiotic resistance due to their overuse and easy access. Beta lactam antibiotics and non beta lactam antibiotics are two major types of antibiotics. CONTENTS 1. Overview and Key Difference 2. What is Beta Lactam 3. What is Non Beta Lactam 4. Similarities Between Beta Lactam and Non Beta Lactam 5.Summary What is Beta Lactam? Beta lactam antibiotics are the antibiotics that contain beta lactam ri...

  PARACETAMOL Paracetamol, also known as acetaminophen and APAP, is a medication used to treat pain and fever. in India, it is available as Brand Name- CALPOL CROCIN T-98   and other It is typically used for mild to moderate pain relief. There is mixed evidence for its use to relieve fever in children. It is often sold in combination with other medications, such as in many cold medications. WINCOLD SUMOCOLD VODACOF HATRIC3 and others Paracetamol is also used for severe pain, such as  cancer pain  and pain after surgery, in combination with  opioid pain medication . It is typically used either by mouth or  rectally , but is also available by  injection into a vein . Effects last between 2 to 4 hours. Paracetamol is generally safe at recommended doses. The recommended maximum daily dose for an adult is 3 or 4 grams. \ Higher doses may lead to toxicity, including  liver failure . Serious skin rashes may rarely occur. It appears to be safe d...